I used to add some Heet to may gas tank every fall just in case. One bottle to 15 - 20 gallons.
With the price of gas being high I was filling up every other month in Missouri and not driving
This week I after the rain and freezing rain I drove the truck 15 minutes, shut down maybe 10 minutes. Restarted and drove a couple miles in town and trouble. After setting 2 hours drove 2 blocks no trouble, after setting 45 minutes restarted and made almost 2 blocks so I stopped and bought 5 bottles of Heet ($7.50) and a new gas filter. I drove home sickly and changed the filter the next morning (after the water quit dripping).
I don't know if the filter passes water of not but a test run was good for the first quarter mile then trouble again.
Today I drove to town again and put in $4 of E85 Gas ($1.85 Gallon) on top of about 17 gallon, it seems to running some better.
The way I figure it. I now have increased the alcohol in the gas from 10% + Heet to 18% + Heet.

I think the E85 for this water removal might be great.

The truck is a 1995 F350 with 5.4L engine and manual transmission.

not completely familiar with your truck and its fuel tank. cars and some trucks that have shown to have the same problems as yours have had a problem with the sock over the fuel pump in the tank to be clogged up. ask a parts guy if yours has this in tank pump. if it does i'll bet its your problem.

Good point on the pickup filter. There is a prefilter to the tank mounted fuel pump. After I put the new in line filter in place I returned the line seperation tool. My after throught was checking flow and pumping the line clear. I guess back to the drawing board.
That one of the problems of being older you don't process information as quickly and darn it engines use to have mechanical fuel pumps and worked off the camshaft.

i had an oldsmobile that would do the same thing. by the time i could get the fuel line off it would pump gas fine and it always had spark. drove me crazy. as for getting older it gets better the older you get. you just don't know it.

Where are you purchasing gasoline that has so much water in it?

I have been buying the gas for the Pickup and Lawn-mower Almost entirely at Sikeston, Missouri area ( normally 20-25 cent cheaper). I bought 30-45 gallons typically when there and seldom ever bought 5 gallon to get back.
We have had a drier winter but had some big damp temperature swings with a lot of condensation on things. Thats my thought on the moisture as I had drove aproxiamately 200 miles on this tank before the problem occurred. Now I'm trying to burn the gas out as I still have 12+ gallons from the Jan 5 fill up.
I'm one of those retired people that could afford the gas at $4 as easily as $2 today so I drive the 30MPG cars as compared to the 12.5 truck.

a call to the dealer you buy from might give you some clues as to whether or not it just your vehicle or every bodies. if its just yours i'm a firm believer in stp gas treatment. don't know about the heat, but i've seen the stp work wonders on some real old trucks. if i'm going to be driving whe its down in the teens i put the stp in to keep the lines from freezing up. never failed me yet.

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I haven't contacted the station yet but will be stopping in this next week.
I have worked the gas out of the tank and everything is back to normal

The puzzling thing I drove about 200 miles in 3 1/2 weeks with no problem durning the use of the first 6 gal. The temp. was however close to freezing. Never had a gas line freeze from it, It got better in steps with about 3 gallon remaining I added 5 gal ran that to about 3 gallon and added 10gal and ran about 40 miles more before power back to normal. Retraining the Computer?
Ran at least another 200 miles the last couple days doing storm cleanup in Metropolis.
I was told things were worst in Kentucky so SUPERMAN was working there.